검색결과 : 39건
| No. | Article |
|---|---|
| 1 |
A Remarkable Difference That One Fluorine Atom Confers on the Mechanisms of Inactivation of Human Ornithine Aminotransferase by Two Cyclohexene Analogues of gamma-Aminobutyric Acid Zhu W, Doubleday PF, Catlin DS, Weerawarna PM, Butrin A, Shen SD, Wawrzak Z, Kelleher NL, Liu DL, Silverman RB Journal of the American Chemical Society, 142(10), 4892, 2020 |
| 2 |
Mechanism of Inactivation of Ornithine Aminotransferase by (1S,3S)-3-Amino-4-(hexafluoropropan-2-ylidenyl)cyclopentane-1-carboxylic Acid Moschitto MJ, Doubleday PF, Catlin DS, Kelleher NL, Liu DL, Silverman RB Journal of the American Chemical Society, 141(27), 10711, 2019 |
| 3 |
Design and Mechanism of GABA Aminotransferase Inactivators. Treatments for Epilepsies and Addictions Silverman RB Chemical Reviews, 118(7), 4037, 2018 |
| 4 |
Design and Mechanism of (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent gamma-Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Addiction Juncosa JI, Takaya K, Le HV, Moschitto MJ, Weerawarna PM, Mascarenhas R, Liu DL, Dewey SL, Silverman RB Journal of the American Chemical Society, 140(6), 2151, 2018 |
| 5 |
beta-Glucocerebrosidase Modulators Promote Dimerization of beta-Glucocerebrosidase and Reveal an Allosteric Binding Site Zheng JB, Chen L, Skinner OS, Ysselstein D, Remis J, Lansbury P, Skerlj R, Mrosek M, Heunisch U, Krapp S, Charrow J, Schwake M, Kelleher NL, Silverman RB, Krainc D Journal of the American Chemical Society, 140(18), 5914, 2018 |
| 6 |
Mechanism of Inactivation of gamma-Aminobutyric Acid Aminotransferase by (1S,3S)-3-Amino-4-difluoromethylene-1-cyclopentanoic Acid (CPP-115) Lee H, Doud EH, Wu R, Sanishvili R, Juncosa JI, Liu DL, Kelleher NL, Silverman RB Journal of the American Chemical Society, 137(7), 2628, 2015 |
| 7 |
Design and Mechanism of Tetrahydrothiophene-Based gamma-Aminobutyric Acid Aminotransferase Inactivators Le HV, Hawker DD, Wu R, Doud E, Widom J, Sanishvili R, Liu DL, Kelleher NL, Silverman RB Journal of the American Chemical Society, 137(13), 4525, 2015 |
| 8 |
Mechanism of Inactivation of Neuronal Nitric Oxide Synthase by (S)-2-Amino-5-(2-(methylthio)acetimidamido)pentanoic Acid Tang W, Li HY, Doud EH, Chen YQ, Choing S, Plaza C, Kelleher NL, Poulos TL, Silverman RB Journal of the American Chemical Society, 137(18), 5980, 2015 |
| 9 |
Temperature-Dependent Spin Crossover in Neuronal Nitric Oxide Synthase Bound with the Heme-Coordinating Thioether Inhibitors (vol 133, pg 8326, 2011) Doukov T, Li HY, Sharma A, Martell JD, Soltis SM, Silverman RB, Poulos TL Journal of the American Chemical Society, 135(18), 7080, 2013 |
| 10 |
Selective Monocationic Inhibitors of Neuronal Nitric Oxide Synthase. Binding Mode Insights from Molecular Dynamics Simulations Huang H, Ji HT, Li HY, Jing Q, Labby KJ, Martasek P, Roman LJ, Poulos TL, Silverman RB Journal of the American Chemical Society, 134(28), 11559, 2012 |