검색결과 : 29건
| No. | Article |
|---|---|
| 1 |
Discovery of Lysine-Targeted eIF4E Inhibitors through Covalent Docking Wan XB, Yang TP, Cuesta A, Pang XM, Balius TE, Irwin JJ, Shoichet BK, Taunton J Journal of the American Chemical Society, 142(11), 4960, 2020 |
| 2 |
Virtual discovery of melatonin receptor ligands to modulate circadian rhythms Stein RM, Kang HJ, McCorvy JD, Glatfelter GC, Jones AJ, Che T, Slocum S, Huang XP, Savych O, Moroz YS, Stauch B, Johansson LC, Cherezov V, Kenakin T, Irwin JJ, Shoichet BK, Roth BL, Dubocovich ML Nature, 579(7800), 609, 2020 |
| 3 |
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing Gordon DE, Jang GM, Bouhaddou M, Xu JW, Obernier K, White KM, O'Meara MJ, Rezelj VV, Guo JFZ, Swaney DL, Tummino TA, Huttenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, Haas K, Modak M, Kim M, Haas P, Polacco BJ, Braberg H, Fabius JM, Eckhardt M, Soucheray M, Bennett MJ, Cakir M, McGregor MJ, Li QY, Meyer B, Roesch F, Vallet T, Mac Kain A, Miorin L, Moreno E, Naing ZZC, Zhou Y, Peng SM, Shi Y, Zhang ZY, Shen WQ, Kirby IT, Melnyk JE, Chorba JS, Lou KV, Dai SZA, Barrio-Hernandez I, Memon D, Hernandez-Armenta C, Lyu J, Mathy CJP, Perica T, Pilla KB, Ganesan SJ, Saltzberg DJ, Rakesh R, Liu X, Rosenthal SB, Calviello L, Venkataramanan S, Liboy-Lugo J, Lin YZ, Huang XP, Liu YF, Wankowicz SA, Bohn M, Safari M, Ugur FS, Koh C, Savar NS, Tran QD, Shengjuler D, Fletcher SJ, O'Neal MC, Cai YM, Chang JCJ, Broadhurst DJ, Klippsten S, Sharp PP, Wenzell NA, Kuzuoglu-Ozturk D, Wang HY, Trenker R, Young JM, Cavero DA, Hiatt J, Roth TL, Rathore U, Subramanian A, Noack J, Hubert M, Stroud RM, Frankel AD, Rosenberg OS, Verba KA, Agard DA, Ott M, Emerman M, Jura N, von Zastrow M, Verdin E, Ashworth A, Schwartz O, D'Enfert C, Mukherjee S, Jacobson M, Malik HS, Fujimori DG, Ideker T, Craik CS, Floor SN, Fraser JS, Gross JD, Sali A, Roth BL, Ruggero D, Taunton J, Kortemme T, Beltrao P, Vignuzzi M, Garcia-Sastre A, Shokat KM, Shoichet BK, Krogan NJ Nature, 583(7816), 459, 2020 |
| 4 |
The activities of drug inactive ingredients on biological targets Pottel J, Armstrong D, Zou L, Fekete A, Huang XP, Torosyan H, Bednarczyk D, Whitebread S, Bhhatarai B, Liang GQ, Jin H, Ghaemi SN, Slocum S, Lukacs KV, Irwin JJ, Berg EL, Giacomini KM, Roth BL, Shoichet BK, Urban L Science, 369(6502), 403, 2020 |
| 5 |
Ultra-large library docking for discovering new chemotypes Lyu J, Wang S, Balius TE, Singh I, Levit A, Moroz YS, O'Meara MJ, Che T, Algaa E, Tolmachova K, Tolmachev AA, Shoichet BK, Roth BL, Irwin JJ Nature, 566(7743), 224, 2019 |
| 6 |
Structural identification of a hotspot on CFTR for potentiation Liu FY, Zhang Z, Levit A, Levring J, Touhara KK, Shoichet BK, Chen J Science, 364(6446), 1184, 2019 |
| 7 |
Colloidal aggregation: From screening nuisance to formulation nuance Ganesh AN, Donders EN, Shoichet BK, Shoichet MS Nano Today, 19, 188, 2018 |
| 8 |
Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone Wang S, Che T, Levit A, Shoichet BK, Wacker D, Roth BL Nature, 555(7695), 269, 2018 |
| 9 |
D-4 dopamine receptor high-resolution structures enable the discovery of selective agonists Wang S, Wacker D, Levit A, Che T, Betz RM, McCorvy JD, Venkatakrishnan AJ, Huang XP, Dror RO, Shoichet BK, Roth BL Science, 358(6361), 381, 2017 |
| 10 |
Hydrogen Bonding of 1,2-Azaborines in the Binding Cavity of T4 Lysozyme Mutants: Structures and Thermodynamics Lee H, Fischer M, Shoichet BK, Liu SY Journal of the American Chemical Society, 138(37), 12021, 2016 |