화학공학소재연구정보센터
검색결과 : 7건
No. Article
1 Serine mutation of a conserved threonine in the hERG K+ channel S6-pore region leads to loss-of-function through trafficking impairment
Al-Moubarak E, Zhang YH, Dempsey CE, Zhang HG, Harmer SC, Hancox JC
Biochemical and Biophysical Research Communications, 526(4), 1085, 2020
2 hERG1a/1b heteromeric currents exhibit amplified attenuation of inactivation in variant 1 short QT syndrome
McPate MJ, Zhang H, Cordeiro JM, Dempsey CE, Witchel HJ, Hancox JC
Biochemical and Biophysical Research Communications, 386(1), 111, 2009
3 Erythromycin block of the HERG K+ channel: Accessibility to F656 and Y652
Duncan RS, Ridley JM, Dempsey CE, Leishman DJ, Leaney JL, Hancox JC, Witchel HJ
Biochemical and Biophysical Research Communications, 341(2), 500, 2006
4 HERG K+ channel blockade by the antipsychotic drug thioridazine: An obligatory role for the S6 helix residue F656
Milnes JT, Witchel HJ, Leaney JL, Leishman DJ, Hancox JC
Biochemical and Biophysical Research Communications, 351(1), 273, 2006
5 The N588K-HERG K+ channel mutation in the'short QT syndrome': Mechanism of gain-in-function determined at 37 degrees C
McPate MJ, Duncan RS, Milnes JT, Witchel HJ, Hancox JC
Biochemical and Biophysical Research Communications, 334(2), 441, 2005
6 Potent inhibition of human cardiac potassium (HERG) channels by the anti-estrogen agent clomiphene - without QT interval prolongation
Yuill KH, Borg JJ, Ridley JM, Milnes JT, Witchel HJ, Paul AA, Kozlowski RZ, Hancox JC
Biochemical and Biophysical Research Communications, 318(2), 556, 2004
7 In silico study of action potential and QT interval shortening due to loss of inactivation of the cardiac rapid delayed rectifier potassium current
Zhang HG, Hancox JC
Biochemical and Biophysical Research Communications, 322(2), 693, 2004