검색결과 : 35건
| No. | Article |
|---|---|
| 1 |
The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs Akinc A, Maier MA, Manoharan M, Fitzgerald K, Jayaraman M, Barros S, Ansell S, Du XY, Hope MJ, Madden TD, Mui BL, Semple SC, Tam YK, Ciufolini M, Witzigmann D, Kulkarni JA, van der Meel R, Cullis PR Nature Nanotechnology, 14(12), 1084, 2019 |
| 2 |
Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA Schlegel MK, Foster DJ, Kel'in AV, Zlatev I, Bisbe A, Jayaraman M, Lackey JG, Rajeev KG, Charisse K, Harp J, Pallan PS, Maier MA, Egli M, Manoharan M Journal of the American Chemical Society, 139(25), 8537, 2017 |
| 3 |
4 '-C-Methoxy-2 '-deoxy-2 '-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing Malek-Adarnian E, Guenther DC, Matsuda S, Martinez-Montero S, Zlatev I, Harp J, Patrascu MB, Foster DJ, Fakhoury J, Perkins L, Moitessier N, Manoharan RM, Taneja N, Bisbe A, Charisse K, Maier M, Rajeev KG, Egli M, Manoharan M, Damha MJ Journal of the American Chemical Society, 139(41), 14542, 2017 |
| 4 |
Orbital Crossings Activated through Electron Injection: Opening Communication between Orthogonal Orbitals in Anionic C1-C5 Cyclizations of Enediynes Peterson PW, Shevchenko N, Breiner B, Manoharan M, Lufti F, Delaune J, Kingsley M, Kovnir K, Alabugin IV Journal of the American Chemical Society, 138(48), 15617, 2016 |
| 5 |
Hybridization Trends for Main Group Elements and Expanding the Bent's Rule Beyond Carbon: More than Electronegativity Alabugin IV, Bresch S, Manoharan M Journal of Physical Chemistry A, 118(20), 3663, 2014 |
| 6 |
Multivalent N-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing Nair JK, Willoughby JLS, Chan A, Charisse K, Alam MR, Wang QF, Hoekstra M, Kandasamy P, Kel'in AV, Milstein S, Taneja N, O'Shea J, Shaikh S, Zhang LG, van der Sluis RJ, Jung ME, Akinc A, Hutabarat R, Kuchimanchi S, Fitzgerald K, Zimmermann T, van Berkel TJC, Maier MA, Rajeev KG, Manoharan M Journal of the American Chemical Society, 136(49), 16958, 2014 |
| 7 |
Direct Observation of the Ion-Pair Dynamics at a Protein-DNA Interface by NMR Spectroscopy Anderson KM, Esadze A, Manoharan M, Bruschweiler R, Gorenstein DG, Iwahara J Journal of the American Chemical Society, 135(9), 3613, 2013 |
| 8 |
Aromatic Transition States in Nonpericyclic Reactions: Anionic 5-Endo Cyclizations Are Aborted Sigmatropic Shifts Gilmore K, Manoharan M, Wu JIC, Schleyer PV, Alabugin IV Journal of the American Chemical Society, 134(25), 10584, 2012 |
| 9 |
Branched Multifunctional Polyether Polyketals: Variation of Ketal Group Structure Enables Unprecedented Control over Polymer Degradation in Solution and within Cells Shenoi RA, Narayanannair JK, Hamilton JL, Lai BFL, Horte S, Kainthan RK, Varghese JP, Rajeev KG, Manoharan M, Kizhakkedathu JN Journal of the American Chemical Society, 134(36), 14945, 2012 |
| 10 |
Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery Lee H, Lytton-Jean AKR, Chen Y, Love KT, Park AI, Karagiannis ED, Sehgal A, Querbes W, Zurenko CS, Jayaraman M, Peng CG, Charisse K, Borodovsky A, Manoharan M, Donahoe JS, Truelove J, Nahrendorf M, Langer R, Anderson DG Nature Nanotechnology, 7(6), 389, 2012 |