검색결과 : 9건
No. | Article |
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1 |
Increased activity of unlinked Zika virus NS2B/NS3 protease compared to linked Zika virus protease Kuiper BD, Slater K, Spellmon N, Holcomb J, Medapureddy P, Muzzarelli KM, Yang Z, Ovadia R, Amblard F, Kovari IA, Schinazi RF, Kovari LC Biochemical and Biophysical Research Communications, 492(4), 668, 2017 |
2 |
Conserved hydrogen bonds and water molecules in MDR HIV-1 protease substrate complexes Liu ZG, Wang Y, Yedidi RS, Dewdney TG, Reiter SJ, Brunzelle JS, Kovari IA, Kovari LC Biochemical and Biophysical Research Communications, 430(3), 1022, 2013 |
3 |
Insights into the mechanism of drug resistance: X-ray structure analysis of multi-drug resistant HIV-1 protease ritonavir complex Liu ZG, Yedidi RS, Wang Y, Dewdney TG, Reiter SJ, Brunzelle JS, Kovari IA, Kovari LC Biochemical and Biophysical Research Communications, 431(2), 232, 2013 |
4 |
Crystallographic study of multi-drug resistant HIV-1 protease lopinavir complex: Mechanism of drug recognition and resistance Liu ZG, Yedidi RS, Wang Y, Dewdney TG, Reiter SJ, Brunzelle JS, Kovari IA, Kovari LC Biochemical and Biophysical Research Communications, 437(2), 199, 2013 |
5 |
Design, synthesis and evaluation of a potent substrate analog inhibitor identified by scanning Ala/Phe mutagenesis, mimicking substrate co-evolution, against multidrug-resistant HIV-1 protease Yedidi RS, Muhuhi JM, Liu ZG, Bencze KZ, Koupparis K, O'Connor CE, Kovari IA, Spaller MR, Kovari LC Biochemical and Biophysical Research Communications, 438(4), 703, 2013 |
6 |
Reduced HIV-1 integrase flexibility as a mechanism resistance Dewdney TG, Wang Y, Kovari IA, Reiter SJ, Kovari LC Journal of Structural Biology, 184(2), 245, 2013 |
7 |
Crystal structures of multidrug-resistant HIV-1 protease in complex with two potent anti-malarial compounds Yedidi RS, Liu ZG, Wang Y, Brunzelle JS, Kovari IA, Woster PM, Kovari LC, Gupta D Biochemical and Biophysical Research Communications, 421(3), 413, 2012 |
8 |
The higher barrier of darunavir and tipranavir resistance for HIV-1 protease Wang Y, Liu ZG, Brunzelle JS, Kovari IA, Dewdney TG, Reiter SJ, Kovari LC Biochemical and Biophysical Research Communications, 412(4), 737, 2011 |
9 |
HIV-1 protease variants from 100-fold drug resistant clinical isolates: expression, purification, and crystallization Vickrey JF, Logsdon BC, Proteasa G, Palmer S, Winters MA, Merigan TC, Kovari LC Protein Expression and Purification, 28(1), 165, 2003 |