화학공학소재연구정보센터
검색결과 : 2건
No. Article
1 Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, Jedrychowski MP, Costa ASH, Higgins M, Hams E, Szpyt J, Runtsch MC, King MS, McGouran JF, Fischer R, Kessler BM, McGettrick AF, Hughes MM, Carroll RG, Booty LM, Knatko EV, Meakin PJ, Ashford MLJ, Modis LK, Brunori G, Sevin DC, Fallon PG, Caldwell ST, Kunji ERS, Chouchani ET, Frezza C, Dinkova-Kostova AT, Hartley RC, Murphy MP, O'Neill LA
Nature, 556(7699), 113, 2018
2 Pharmacokinetics and pharmacodynamics of orally administered acetylenic tricyclic bis(cyanoenone), a highly potent Nrf2 activator with a reversible covalent mode of action
Kostov RV, Knatko EV, McLaughlin LA, Henderson CJ, Zheng S, Huang JTJ, Honda T, Dinkova-Kostova AT
Biochemical and Biophysical Research Communications, 465(3), 402, 2015