| 1 |
Hydrogen-Deuterium Exchange within Adenosine Deaminase, a TIM Barrel Hydrolase, Identifies Networks for Thermal Activation of Catalysis (vol 142, pg 19936, 2020)
Gao SH, Thompson EJ, Barrow SL, Zhang WJ, Iavarone AT, Klinman JP
Journal of the American Chemical Society, 143(7), 3013, 2021 |
| 2 |
Identification of Thermal Conduits That Link the Protein-Water Interface to the Active Site Loop and Catalytic Base in Enolase
Thompson EJ, Paul A, Iavarone AT, Klinman JP
Journal of the American Chemical Society, 143(2), 785, 2021 |
| 3 |
Structural Properties and Catalytic Implications of the SPASM Domain Iron-Sulfur Clusters in Methylorubrum extorquens PqqE
Zhu W, Walker LM, Tao LZ, Iavarone AT, Wei XT, Britt RD, Elliott SJ, Klinman JP
Journal of the American Chemical Society, 142(29), 12620, 2020 |
| 4 |
Detecting and Characterizing the Kinetic Activation of Thermal Networks in Proteins: Thermal Transfer from a Distal, Solvent-Exposed Loop to the Active Site in Soybean Lipoxygenase
Zaragoza JPT, Nguy A, Minnetian N, Deng ZY, Iavarone AT, Offenbacher AR, Klinman JP
Journal of Physical Chemistry B, 123(41), 8662, 2019 |
| 5 |
Biophysical Characterization of a Disabled Double Mutant of Soybean Lipoxygenase: The "Undoing" of Precise Substrate Positioning Relative to Metal Cofactor and an Identified Dynamical Network
Hu SS, Offenbacher AR, Thompson EM, Gee CL, Wilcoxen J, Carr CAM, Prigozhin DM, Yang V, Alber T, Britt RD, Fraser JS, Klinman JP
Journal of the American Chemical Society, 141(4), 1555, 2019 |
| 6 |
Discovery of Hydroxylase Activity for PqqB Provides a Missing Link in the Pyrroloquinoline Quinone Biosynthetic Pathway
Koehn EM, Latham JA, Armand T, Evans RL, Tu XY, Wilmot CM, Iavarone AT, Klinman JP
Journal of the American Chemical Society, 141(10), 4398, 2019 |
| 7 |
Activity-Related Microsecond Dynamics Revealed by Temperature-Jump Forster Resonance Energy Transfer Measurements on Thermophilic Alcohol Dehydrogenase
Vaughn MB, Zhang JY, Spiro TG, Dyer RB, Klinman JP
Journal of the American Chemical Society, 140(3), 900, 2018 |
| 8 |
C-13 ENDOR Spectroscopy of Lipoxygenase-Substrate Complexes Reveals the Structural Basis for C-H Activation by Tunneling
Horitani M, Offenbacher AR, Carr CAM, Yu T, Hoeke V, Cutsail GE, Hammes-Schiffer S, Klinman JP, Hoffman BM
Journal of the American Chemical Society, 139(5), 1984, 2017 |
| 9 |
Origins of Enzyme Catalysis: Experimental Findings for C-H Activation, New Models, and Their Relevance to Prevailing Theoretical Constructs
Klinman JP, Offenbacher AR, Hu SS
Journal of the American Chemical Society, 139(51), 18409, 2017 |
| 10 |
How Large Should the QM Region Be in QM/MM Calculations? The Case of Catechol O-Methyltransferase
Kulik HJ, Zhang JY, Klinman JP, Martinez TJ
Journal of Physical Chemistry B, 120(44), 11381, 2016 |
