검색결과 : 7건
No. | Article |
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1 |
Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death Garcia-Bermudez J, Baudrier L, Bayraktar EC, Shen YH, La K, Guarecuco R, Yucel B, Fiore D, Tavora B, Freinkman E, Chan SH, Lewis C, Min W, Inghirami G, Sabatini DM, Birsoy K Nature, 567(7746), 118, 2019 |
2 |
Histidine catabolism is a major determinant of methotrexate sensitivity Kanarek N, Keys HR, Cantor JR, Lewis CA, Chan SH, Kunchok T, Abu-Remaileh M, Freinkman E, Schweitzer LD, Sabatini DM Nature, 559(7715), 632, 2018 |
3 |
LACTB is a tumour suppressor that modulates lipid metabolism and cell state Keckesova Z, Donaher JL, De Cock J, Freinkman E, Lingrell S, Bachovchin DA, Bierie B, Tischler V, Noske A, Okondo MC, Reinhardt F, Thiru P, Golub TR, Vance JE, Weinberg RA Nature, 543(7647), 681, 2017 |
4 |
Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes Abu-Remaileh M, Wyant GA, Kim C, Laqtom NN, Abbasi M, Chan SH, Freinkman E, Sabatini DM Science, 358(6364), 807, 2017 |
5 |
Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers Mayers JR, Torrence ME, Danai LV, Papagiannakopoulos T, Davidson SM, Bauer MR, Lau AN, Ji BW, Dixit PD, Hosios AM, Muir A, Chin CR, Freinkman E, Jacks T, Wolpin BM, Vitkup D, Vander Heiden MG Science, 353(6304), 1161, 2016 |
6 |
SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance Kim D, Fiske BP, Birsoy K, Freinkman E, Kami K, Possemato RL, Chudnovsky Y, Pacold ME, Chen WW, Cantor JR, Shelton LM, Gui DY, Kwon M, Ramkissoon SH, Ligon KL, Kang SW, Snuderl M, Vander Heiden MG, Sabatini DM Nature, 520(7547), 363, 2015 |
7 |
Cytoplasmic ATP Hydrolysis Powers Transport of Lipopolysaccharide Across the Periplasm in E-coli Okuda S, Freinkman E, Kahne D Science, 338(6111), 1214, 2012 |