검색결과 : 9건
| No. | Article |
|---|---|
| 1 |
Activation of the GLP-1 receptor by a non-peptidic agonist Zhao PS, Liang YL, Belousoff MJ, Deganutti G, Fletcher MM, Willard FS, Bell MG, Christe ME, Sloop KW, Inoue A, Truong TT, Clydesdale L, Furness SGB, Christopoulos A, Wang MW, Miller LJ, Reynolds CA, Danev R, Sexton PM, Wootten D Nature, 577(7790), 432, 2020 |
| 2 |
Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex Liang YL, Khoshouei M, Glukhova A, Furness SGB, Zhao PS, Clydesdale L, Koole C, Truong TT, Thal DM, Lei SF, Radjainia M, Danev R, Baumeister W, Wang MW, Miller LJ, Christopoulos A, Sexton PM, Wootten D Nature, 555(7694), 121, 2018 |
| 3 |
Structural insights into G-protein-coupled receptor allostery Thal DM, Glukhova A, Sexton PM, Christopoulos A Nature, 559(7712), 45, 2018 |
| 4 |
Structure of the adenosine-bound human adenosine A(1) receptor-G(i) complex Draper-Joyce CJ, Khoshouei M, Thal DM, Liang YL, Nguyen ATN, Furness SGB, Venugopal H, Baltos JA, Plitzko JM, Danev R, Baumeister W, May LT, Wootten D, Sexton PM, Glukhova A, Christopoulos A Nature, 558(7711), 559, 2018 |
| 5 |
Cryo-EM structure of the active, G(s)- protein complexed, human CGRP receptor Liang YL, Khoshouei M, Deganutti G, Glukhova A, Koole C, Peat TS, Radjainia M, Plitzko JM, Baumeister W, Miller LJ, Hay DL, Christopoulos A, Reynolds CA, Wootten D, Sexton PM Nature, 561(7724), 492, 2018 |
| 6 |
Allostery and Biased Agonism at Class B G Protein-Coupled Receptors Wootten D, Miller LJ, Koole C, Christopoulos A, Sexton PM Chemical Reviews, 117(1), 111, 2017 |
| 7 |
Phase-plate cryo-EM structure of a class B GPCR-G-protein complex Liang YL, Khoshouei M, Radjainia M, Zhang Y, Glukhova A, Tarrasch J, Thal DM, Furness SGB, Christopoulos G, Coudrat T, Danev R, Baumeister W, Miller LJ, Christopoulos A, Kobilka BK, Wootten D, Skiniotis G, Sexton PM Nature, 546(7656), 118, 2017 |
| 8 |
Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs Dror RO, Green HF, Valant C, Borhani DW, Valcourt JR, Pan AC, Arlow DH, Canals M, Lane JR, Rahmani R, Baell JB, Sexton PM, Christopoulos A, Shaw DE Nature, 503(7475), 295, 2013 |
| 9 |
Activation and allosteric modulation of a muscarinic acetylcholine receptor Kruse AC, Ring AM, Manglik A, Hu JX, Hu K, Eitel K, Hubner H, Pardon E, Valant C, Sexton PM, Christopoulos A, Felder CC, Gmeiner P, Steyaert J, Weis WI, Garcia KC, Wess J, Kobilka BK Nature, 504(7478), 101, 2013 |