| 1 |
Attenuating apoptosis in Chinese hamster ovary cells for improved biopharmaceutical production
Henry MN, MacDonald MA, Orellana CA, Gray PP, Gillard M, Baker K, Nielsen LK, Marcellin E, Mahler S, Martinez VS
Biotechnology and Bioengineering, 117(4), 1187, 2020 |
| 2 |
Unraveling what makes a monoclonal antibody difficult-to-express: From intracellular accumulation to incomplete folding and degradation via ERAD
Mathias S, Wippermann A, Raab N, Zeh N, Handrick R, Gorr I, Schulz P, Fischer S, Gamer M, Otte K
Biotechnology and Bioengineering, 117(1), 5, 2020 |
| 3 |
Identifying low-level sequence variants via next generation sequencing to aid stable CHO cell line screening
Zhang S, Bartkowiak L, Nabiswa B, Mishra P, Fann J, Ouellette D, Correia I, Regier D, Liu JJ
Biotechnology Progress, 31(4), 1077, 2015 |
| 4 |
IL-17F co-expression improves cell growth characteristics and enhances recombinant protein production during CHO cell line engineering
Contie M, Leger O, Fouque N, Poitevin Y, Kosco-Vilbois M, Mermod N, Elson G
Biotechnology and Bioengineering, 110(4), 1153, 2013 |
| 5 |
Transgene copy number distribution profiles in recombinant CHO cell lines revealed by single cell analyses
He LH, Winterrowd C, Kadura I, Frye C
Biotechnology and Bioengineering, 109(7), 1713, 2012 |
| 6 |
Overexpression of survivin and cyclin D1 in CHO cells confers apoptosis resistance and enhances growth in serum-free suspension culture
Zhao XH, Guo JW, Yu YQ, Yi SQ, Yu T, Fu L, Hou LH, Chen W
Biotechnology Letters, 33(7), 1293, 2011 |
| 7 |
Characterization of the Proteases Involved in the N-Terminal Clipping of Glucagon-Like-Peptide-1-Antibody Fusion Proteins
Dorai H, Santiago A, Campbell M, Tang QM, Lewis MJ, Wang YH, Lu QZ, Wu SL, Hancock W
Biotechnology Progress, 27(1), 220, 2011 |
| 8 |
Expression of GnTIII in a recombinant anti-CD20 CHO production cell line: Expression of antibodies with altered glycoforms leads to an increase in ADCC through higher affinity for Fc gamma RIII
Davies J, Jiang LY, Pan LZ, LaBarre MJ, Anderson D, Reff M
Biotechnology and Bioengineering, 74(4), 288, 2001 |
| 9 |
Correction of glycogen storage disease type II by enzyme replacement with a recombinant human acid maltase produced by over-expression in a CHO-DHFRneg cell line
Martiniuk F, Chen A, Donnabella V, Arvanitopoulos E, Slonim AE, Raben N, Plotz P, Rom WN
Biochemical and Biophysical Research Communications, 276(3), 917, 2000 |
