| 1 |
Phosphodianion Activation of Enzymes for Catalysis of Central Metabolic Reactions
Fernandez PL, Nagorski RW, Cristobal JR, Amyes TL, Richard JP
Journal of the American Chemical Society, 143(7), 2694, 2021 |
| 2 |
Uncovering the Role of Key Active-Site Side Chains in Catalysis: An Extended Bronsted Relationship for Substrate Deprotonation Catalyzed by Wild-Type and Variants of Triosephosphate Isomerase
Kulkarni YS, Amyes TL, Richard J, Kamerlin SCL
Journal of the American Chemical Society, 141(40), 16139, 2019 |
| 3 |
Role of the Carboxylate in Enzyme-Catalyzed Decarboxylation of Orotidine 5 '-Monophosphate: Transition State Stabilization Dominates Over Ground State Destabilization
Goryanova B, Amyes TL, Richard JP
Journal of the American Chemical Society, 141(34), 13468, 2019 |
| 4 |
Role of Ligand-Driven Conformational Changes in Enzyme Catalysis: Modeling the Reactivity of the Catalytic Cage of Triosephosphate Isomerase
Kulkarni YS, Liao QH, Bylehn F, Amyes TL, Richard JP, Kamerlin SCL
Journal of the American Chemical Society, 140(11), 3854, 2018 |
| 5 |
Enzyme Architecture: Amino Acid Side-Chains That Function To Optimize the Basicity of the Active Site Glutamate of Triosephosphate Isomerase
Zhai X, Reinhardt CJ, Malabanan MM, Amyes TL, Richard JP
Journal of the American Chemical Society, 140(26), 8277, 2018 |
| 6 |
Enzyme Architecture: Breaking Down the Catalytic Cage that Activates Orotidine 5 '-Monophosphate Decarboxylase for Catalysis
Reyes AC, Plache DC, Koudelka AP, Amyes TL, Gerlt JA, Richard JP
Journal of the American Chemical Society, 140(50), 17580, 2018 |
| 7 |
Enzyme Architecture: Modeling the Operation of a Hydrophobic Clamp in Catalysis by Triosephosphate Isomerase
Kulkarni YS, Liao QH, Petrovic D, Kruger DM, Strodel B, Amyes TL, Richard JP, Kamerlin SCL
Journal of the American Chemical Society, 139(30), 10514, 2017 |
| 8 |
Enzyme Architecture: Erection of Active Orotidine 5'-Monophosphate Decarboxylase by Substrate-Induced Conformational Changes
Reyes AC, Amyes TL, Richard JP
Journal of the American Chemical Society, 139(45), 16048, 2017 |
| 9 |
Structure-Reactivity Effects on Intrinsic Primary Kinetic Isotope Effects for Hydride Transfer Catalyzed by Glycerol-3-phosphate Dehydrogenase
Reyes AC, Amyes TL, Richard JP
Journal of the American Chemical Society, 138(44), 14526, 2016 |
| 10 |
Enzyme Architecture: Self-Assembly of Enzyme and Substrate Pieces of Glycerol-3-Phosphate Dehydrogenase into a Robust Catalyst of Hydride Transfer
Reyes AC, Amyes TL, Richard JP
Journal of the American Chemical Society, 138(46), 15251, 2016 |
