화학공학소재연구정보센터
학회 한국재료학회
학술대회 2011년 가을 (10/27 ~ 10/29, 신라대학교)
권호 17권 2호
발표분야 B. Nanomaterials and Processing Technology(나노소재기술)
제목 Synthesis of Silver Nanowire-DNA Conjugates for Sensitive Diagnostic Applications
초록 We have synthesized silver nanowire-DNA conjugates and have designed a target DNA-detection system in which the silver nanowire-DNA conjugates and gold nanoparticle-DNA conjugates are complementary to each half of target sequence. In the presence of the target, the gold nanoparticle-DNA conjugates are supposed to hybridize onto the silver nanowire-DNA conjugates, whose quantity would be proportional to the target concentration and could be analyzed by simply counting the particles on the nanowires in the SEM images. The limit of detection is determined to be 50 pM. This system can also selectively and efficiently discriminate a one-base mismatch target from perfect match target.
저자 한상헌, 이재승
소속 고려대
키워드 silver nanowire; detection
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