| 초록 |
Catechol functional group of dopamine (3,4-dihydroxyphenethylamine, DOP) has been known for the ability to form strong adhesive bonds to both inorganic and organic surfaces in aqueous environments, and the related dopamine chemistry was well documented recently. Polyaspartamides is a biocompatible water-soluble poly(amino acid), which has been extensively studied for biomedical and pharmaceutical applications. Adhesion and oxidative crosslinking of DOP-conjugated polyaspartamides can provide a way to modify various material surfaces (synthetic polymer, metals, metal oxides, ceramic) in aqueous environment. Here we demonstrate a versatile coating for material-independent surface modification using poly(amino acid)s conjugated with dopamine. These novel functional polymers have potential for use in many technological fields including industrial and medical adhesives, surface modifications of biomaterials, etc. |
