초록 |
Nature utilizes non-covalent interactions to form functional entities like cell membrane or protein macrostructures. Herein, nature’s strategy was employed to design self-assembling peptoid amphiphiles. Helical rod-coil motif has rarely been exploited in peptoid amphihpiles. The peptoid amphiphiles composed of helical rod and unstructured coil enabled the complete dissolution of the assembled structure in an aqueous media. Surfactant-like property such as foaming was observed as well. Critical micelle concentration of each peptoid was evaluated, and the size of structures in solution was measured by dynamic light scattering (DLS). Hierarchical self-assembled structures were observed by scanning electron microscopy (SEM). The peptoid amphiphiles provided various self-assembled architectures such as sphere, fiber, and lamella in water. |