| 학회 |
한국공업화학회 |
| 학술대회 |
2017년 봄 (05/10 ~ 05/12, 광주 김대중컨벤센센터(Kimdaejung Convention Center)) |
| 권호 |
21권 1호 |
| 발표분야 |
고분자 |
| 제목 |
Near infrared light-responsive core cross-linked polymeric micelles of poly(ethylene oxide)-b-poly(glycidyl methacrylate) utilizing diselenide cross-linker |
| 초록 |
In this study, near infrared light-responsive core cross-linked micelles of poly(ethylene oxide)-b-poly(glycidyl methacrylate) (PEO-b-PGMA) block copolymers were prepared by a diselenide cross-linker using click chemistry. Diblock copolymers of PEO-b-PGMA were synthesized by the RAFT polymerization and subsequently were functionalized with azide groups. The micelles of azido functional PEO-b-PGMA-(N3) were cross-linked by dipropargyl 3,3’diselanedyldipropionate in the presence of copper(II) sulfate pentahydrate and sodium ascorbate using alkyne-azide click reaction. The block copolymers and cross-linked micelle were characterized by using gel permeation chromatography, fourier-transform infrared spectroscopy, 1H nuclear magnetic resonance, and dynamic light scattering analysis. The core cross-liked micelle presented a stable structure and cleavage of diselenium bond occurred in the presence of reactive oxygen species under near infrared light irradiation. |
| 저자 |
서용성, 임권택, Salma Sabrina Aufar, Cuong M.Q. Le
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| 소속 |
부경대 |
| 키워드 |
click chemistry; RAFT polymerization; core cross-linked micelles; NIR responsive
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| E-Mail |
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