| 학회 |
한국고분자학회 |
| 학술대회 |
2014년 봄 (04/10 ~ 04/11, 대전 컨벤션센터) |
| 권호 |
39권 1호 |
| 발표분야 |
의료용 고분자 부문위원회(초청-영어발표/포스터-국문발표 가능) |
| 제목 |
The Study of SIS/PLGA Scaffolds and Costal Cartilage Cells for Cartilage Regeneration In vitro and In vivo |
| 초록 |
Various contents SIS/PLGA scaffolds were fabricated and confirmed that according to different SIS content; 0, 10, 20, 40 and 80 wt%. Assays of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and scanning electron microscope (SEM) carried out to measure the attachment and proliferation of costal cartilage cells (CCs) in SIS/PLGA scaffolds. Glycosaminoglycan (sGAG) and collagen contents assay were conducted to confirm effects of SIS on formulation extra cellular matrix (ECM). And RT-PCR was carried out and immunohistochemistry staining was conducted to confirm the CCs specific genetic marker. In this study demonstrated that 20 wt% SIS/PLGA scaffolds showed positive effects on cell growth and proliferation. This research was supported by NRF-2012M3A9C6050204, Bio-industry Technology Development Program (KMFAFF, 112007-05-2-SB010) and the Brain Korea 21 PLUS Project, NRF. |
| 저자 |
이천중, 차세롬, 김수영, 김은영, 송정은, 강길선
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| 소속 |
전북대 |
| 키워드 |
SIS; Poly (lactic-co-glycolic acid) (PLGA); Costal Cartilage
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| E-Mail |
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