화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2014년 가을 (10/06 ~ 10/08, 제주 ICC)
권호 39권 2호
발표분야 의료용 고분자 부문위원회
제목 Amphiphilic Peptide Nanofibers for Biomedical Application
초록 Nano structures formed from self-assembly of organic and inorganic building blocks have drawn much attention in the field of biology and chemistry due to its potential applications in biomaterials. Among them, peptides have gained much attraction because of its chemical diversity and bio degradability. Peptides have intrinsic ability to form well ordered nano-structures such as fibers, tubes, cages, vesicle, etc. through the self-assembly based on formation of secondary structure and other specific interactions which can find application in tissue engineering, drug delivery, wound healing as biomaterials. In this present work, we introduce nanofibers formed by positively charged peptide amphiphiles. These nanofibers exhibit well defind morphological changes upon conjugation with porphyrine containing tetra carboxylic acid by electrostatic interaction. These nano structures can find application in the area of photodynamic therapy in drug delivery system.
저자 Jeena Manayath Thekkeyil, 유자형
소속 Ulsan National Institute of Science and Technology
키워드 peptide amphiphile; self assembly; nanofiber; biomedical application
E-Mail jhryu@unist.ac.kr