| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 가을 (10/06 ~ 10/08, 대구컨벤션센터(EXCO)) |
| 권호 |
40권 2호 |
| 발표분야 |
고분자합성 |
| 제목 |
Ring-opening polymerization of α-Amino acid N-Carboxyanhydrides by Employing Carbene Derivatives as a Catalyst |
| 초록 |
A series of polypeptides have been synthesized by ring-opening polymerization of α-amino acid N-carboxyanhydride (NCA) by using 1,3-diisopropylimidazolium hydrogen carbonate as the catalyst. The catalyst was achieved by anion metathesis of imidazolium halides using potassium hydrogen carbonate in methanolic solution, without the need for the prior preparation of free carbene. With this methodology, the ring-opening polymerization of polypeptides are controllable and faster. The control of polymerization was attributed to the strong nucleophilicity of N-heterocyclic carbenes. |
| 저자 |
김일1, 류런제2
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| 소속 |
1BK21플러스동남권화학신기술창의인재양성사업단, 2부산대 |
| 키워드 |
Polypeptide; α-amino acid N-carboxyanhydride; N-heterocyclic carbenes; Ring-opening polymerization
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| E-Mail |
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