화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2017년 봄 (05/10 ~ 05/12, 광주 김대중컨벤센센터(Kimdaejung Convention Center))
권호 21권 1호
발표분야 콜로이드계면화학
제목 Visualization of Phase Behavior of Freestanding, Planar, and Asymmetric Lipid Bilayer
초록 Asymmetry of outer and inner leaflet is important feature of cell membrane because it relates to fundamental biological processes. In this work, we made freestanding and planar lipid bilayer that has hundreds of micrometers in dimeter by lipid-in method. We developed the shoring structure made by 3D printing for stable bilayer formation. We found that asymmetric bilayers had different phase behavior depending on lipid composition and temperature compared to symmetric bilayer. Moreover, we understood the effect of asymmetry on domain size and verified its thermodynamics by Landau model.
저자 이현로, 이요한, 최시영
소속 KAIST
키워드 Lipid bilayer; Phase separation; Landau model
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