| 초록 |
Gelatin, derived from the hydrolysis of collagen, has great advantages of biocompatibility and biodegradability. However intrinsic weak water-stability and mechanical properties has limited the utilization. Up to now, to overcome these weakness, chemical cross-linker such as glutaraldehyde and genipin has been attempted. However, these are neither cost-effective and environmentally friendly. In this study, alginate di-aldehyde (ADA) was prepared and used as a green cross-linker to fabricate water-insoluble gelatin films. The cross-linking reaction and physicochemical properties of gelatin/ADA bio-composite film were confirmed by FE-SEM, FTIR, and XPS. The mechanical and hydrophilic properties were evaluated by tensile test and contact angle, swelling ratio, and total soluble matter measurement. From the results, ADA enabled the cross-linking process via Schiff base formation. Furthermore, tensile properties and water stability could be easily controllable by addition amount of ADA. |
