화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2017년 봄 (04/05 ~ 04/07, 대전컨벤션센터)
권호 42권 1호
발표분야 의료용 고분자 부문위원회 I
제목 Silymarin/Duck’s feet-derived Collagen/Hydroxyapatite 3D Scaffold for Bone Tissue Regeneration
초록 Silymarin is a constitutive natural compound composed of an isomeric mixture of flavonolignans of silychristin, iso-silychristin, silydianin, silibinin and isosilibin. Silymarin is abundant in milk thisle (silybum marianum) and has been clinically applied for various liver diseases such as alcohol or drug intoxication and viral hepatitis, whose pathogenesis involves an inflammatory response. Collagen is mainly used for cartilage, bone and skin regeneration owing to its well-known biocompatibility, biodegradability, low antigenicity, hemostatic effect, and cell adhesion. The aim of this study was to fabricate three dimensional (3D) Smn/DC/HAp scaffolds and access its availability for bone grafts through in vitro and in vivo test.
저자 박현, 전유신, 이대훈, 심보라, 전하얀, 국연지, 김한솔, 송정은, 강길선
소속 전북대
키워드 Silymarin; Scaffold; Bone marrow stem cell; Collagen; Tissue engineering
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