| 초록 |
Novel bifunctional fluorescent magneto polymeric nanoprobes (FMPNs) were synthesized to provide simultaneous diagnosis information via magnetic resonance imaging (MRI) and optical imaging. FMPNs consist of ultra-sensitive magnetic nanocrystals as MR probes and Nile Red as fluorescent probe were encapsulated in polyvinyl alcohol (PVA, 87~89% hydrolyzed) through the medium matrix of well synthesized poly methyl methacrylate (PMMA) by nano-emulsion method. FMPNs exhibited excellent colloidal stability and monodispersity. And the MR and optical images, also, clearly demonstrated that FMPNs has potential as an unltrasensitive dual-mode imaging agents. |
