| 학회 |
한국화학공학회 |
| 학술대회 |
2006년 가을 (10/27 ~ 10/28, 고려대학교) |
| 권호 |
12권 2호, p.1446 |
| 발표분야 |
공업화학 |
| 제목 |
Biomolecular Purification with Aminosilanes Anchored Mesoporous Silicas |
| 초록 |
The work describes the innovative development of high throughput human DNA and protein purification using the molecular self-assembled mesoporous silicas. The synthesis of mesoporous silicas was involved a sol-gel process, and the formation of aminofunctionalized monolayers was chemically grafted. The target DNA and proteins were used from human blood, and commercialized lysozyme, respectively. The result showed the optimum effect on the number of aminofunctional groups, their recovery efficiency was enhanced to 90%~100%. The use of functionalized mesoporous silica for DNA and protein purification process give a lot of advantages rather than use of conventional silica based materials. |
| 저자 |
조민애1, 장정호2, 김우년3
|
| 소속 |
1한국요업(세라믹)기술원 나노소재응용본부 / 고려대, 2한국요업(세라믹)기술원 나노소재응용본부, 3고려대 |
| 키워드 |
DNA; PROTEIN
|
| E-Mail |
|
| 원문파일 |
초록 보기 |
