| 학회 |
한국공업화학회 |
| 학술대회 |
2008년 봄 (05/09 ~ 05/10, 한양대학교(안산)) |
| 권호 |
12권 1호 |
| 발표분야 |
생물공학 |
| 제목 |
Reaction medium engineering for an efficient kinetic resolution of racemic styrene oxide at high concentration |
| 초록 |
The theoretical yield of kinetic resolution cannot exceed 50%. Despite this drawback, kinetic resolution processes are still one of the major methods for the industrial production of chiral compounds. In order to enhance the efficiency of kinetic resolution of racemic styrene oxide by epoxide hydrolase, the effects of addition of detergent and glycerol were investigated. Chiral styrene oxide with 100 %ee could be prepared from high initial concentration of racemic styrene oxide at the optimized concentrations of surfactant and glycerol. Acknowledgment: This work was partially supported by the Marine and Extreme Genome Research Center Program, Ministry of Marine Affairs and Fisheries, Korea. |
| 저자 |
이경화1, 박성훈2, 김희숙3, 박창호1, 이은열1
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| 소속 |
1경희대, 2부산대, 3경성대 |
| 키워드 |
medium reaction engineering; detergent; glycerol; chiral styrene oxide
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| E-Mail |
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