| 초록 |
A major challenge in surface-enhanced Raman spectroscopy (SERS) for sensing application is to make a substrate structure which has high and reproducible signal enhancement effect. Bacteriophage-based nanostructure has a potential for SERS substrate, due to its highly regular self-assembling property and diverse surface functional groups for chemical modification. In this work, Bacteriophage MS2 was used as a template for making highly-ordered assembly of gold nanoparticles into a plasmonic 'nanohalo' structures. Surface lysine groups were functionalized with linker to regularly orient the gold nanoparticles, which makes reproducible plasmon coupling effect and hence SERS signal enhancement. |
