화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2021년 봄 (05/12 ~ 05/14, 부산 벡스코(BEXCO))
권호 25권 1호
발표분야 포스터-생체재료
제목 Near-infrared light-triggered photodynamic therapy using core-shell structured upconversion nanoparticles with dual photosensitizers
초록 Recently, rare earth-doped upconversion nanoparticles (UCNPs) have been widely studied for near-infrared (NIR)-triggered photodynamic therapy (PDT). UCNP has advantages, such as non-autofluorescence background with high signal-to-noise ratio, high photostability, non-blinking and non-bleaching of upconversion luminescence (UCL), and deep penetration in deep tissue. In this study, we synthesized the neodymium-doped UCNPs with a core-shell structure by thermal decomposition method. The surface modification of UCNPs was demonstrated for bioimaging and PDT applications. The size, size distribution, crystalline morphology, photoluminescence properties and PDT effects of the surface-modified UCNPs were also investigated.  
저자 최종선, 김소연
소속 충남대
키워드 upconversion nanoparticle; bioimaging; photodynamic therapy; core-shell structure; deep penetration
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