초록 |
Recently, rare earth-doped upconversion nanoparticles (UCNPs) have been widely studied for near-infrared (NIR)-triggered photodynamic therapy (PDT). UCNP has advantages, such as non-autofluorescence background with high signal-to-noise ratio, high photostability, non-blinking and non-bleaching of upconversion luminescence (UCL), and deep penetration in deep tissue. In this study, we synthesized the neodymium-doped UCNPs with a core-shell structure by thermal decomposition method. The surface modification of UCNPs was demonstrated for bioimaging and PDT applications. The size, size distribution, crystalline morphology, photoluminescence properties and PDT effects of the surface-modified UCNPs were also investigated. |