| 초록 |
Bone substitutes for the treatment of bones of aging and various causes are important biomaterials. Trace elements together with calcium and phosphate are known to contribute to the formation of HA. In this study, the effects of the combination of CaP with trace elements on the proliferation and differentiation of osteoblastic MG63 cells were analyzed. Morphological changes in CaP particle and resulting effect on pore shape were observed using a SEM, and the constituent elements were confirmed by an EDX. Then, changes in water uptake, decomposition, and pH due to changes in pores and chemical composition were investigated. In addition, qualitative analysis of elements was performed using an FTIR. Growth and differentiation of MG63 cells were evaluated. |
