화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2019년 봄 (05/01 ~ 05/03, 부산 벡스코(BEXCO))
권호 23권 1호
발표분야 생체재료_포스터
제목 Fabrication of Nanodiamond-Containing Poly (ε-caprolactone) Fiber Matrices Using Electrospinning for Bone Medical
초록 We have fabricated a fibrous poly(ε-caprolactone) (PCL) matrices containing nanodiamond (ND) using a electrospinning process for bone medical. The PCL matrices contained with ND (ND/PCL) was prepared with different ND concentrations (0.5, 1, 2, and 3 wt%) to give optimum tensile properties and precursor activity. The ND/PCL matrix containing 1 wt% ND showed the highest Young's modulus and tensile strength through the universal testing machine (UTM) test results. In vitro cell experiments were carried out using mouse fibroblast (NIH/3T3) and mouse calbria-derived pioneer cell line (MC3T3-E1) to find that the ND/PCL matrix containing 1% Proliferation. The ND/PCL matrix containing 1 wt% ND increased the highest alkaline phosphate activity and calcium deposition on the matrix. The ND/PCL matrix with high tensile strength and positive preosteoblast activity is a promising material for bone regeneration and dental tissue engineering.
저자 안국영, 최성욱
소속 가톨릭대
키워드 Nanodiamond; Biodegradable polymer; Composite; Tissue engineering
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