| 초록 |
For the increasing demand of soft materials with wide range of applications, hydrogels have been developed exhibiting variety of functions. In general, most hydrogels have been designed by multiple component to achieve some functionalities. Multi-conponent systems often requires tremendous labors during preperation process and accompany undesirable reactions that can be avoidable in single component hydrogel system. Here, we developed single component hydrogel, alginate-boronic acid hydrogel, that can exhibit unprecedented multi-functionalities simultaneously such as high stretchable, self-healing, shear-thinning, pH- and glucose-sensitivities, adhesive, and re-shaping properties. Multi-functionalities of alginate-BA hydrogel is resulted from the reversible inter-, intra-molecular interactions by dynamic equilibrium of boronic acid-diol complexation and dissociation. These findings suggest that this novel hydrogel have potentials for use in wide range of biomedical applications. |
