화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2018년 가을 (10/10 ~ 10/12, 경주컨벤션센터)
권호 43권 2호
발표분야 의료용 고분자 부문위원회 II
제목 Broadening pH Window by DNA Hydrogel Composed of Polyacid and Non-canonical DNA
초록 Polymer has played an important role as an organic material, and its property of responsiveness to stimuli such as temperature, pH, ion and light has drawn attention for applications as a smart material. DNA also has been an interesting subject as an organic material itself as well as a programmable gene code; its properties such as target-specific capturing and pH-responsiveness have been studied. Even though various studies have been reported to relate these two different fields, they still have a good many things to find inbetween. Here, we synthesized a hybrid gel with polymer backbones and DNA moieties having pH-responsive properties both. This hybrid gel is obtained by sol-gel transition in pH showing swelling and shrinking behaviors. By this study, we report a new mean of pH-responsive system by the polymer-based DNA hybrid gel suggesting its potential in the fields of controlled drug delivery, sensors, actuators, nano-machine, and microfluidics.
저자 김혜진, 김진곤, 오승수
소속 포항공과대
키워드 hydrogel; copolymer; pH; polyacid; DNA; non-canonical
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