| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 봄 (04/08 ~ 04/10, 대전컨벤션센터) |
| 권호 |
40권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Fabrication of Microarchitecture Consist of PEG Hydrogel and PCL Nanofiber for Cell Encapsulation and Protein Delivery |
| 초록 |
Well defined micro-scale architecture composed of electrospun PCL nanofibers and photopatterned PEG polymer hydrogel was fabricated by simple method. Possible applications are cell encapsulation and protein delivery. Cell encapsulation for providing 3D environment, cell adhesion and bioassay has got interest in tissue engineering field. On the other hand, Protein delivery to specific tissue region is important issue, especially in drug delivery system area. To deliver protein, injection of carrier which loaded with protein, with gradual release property is studied widely. In this study, hydrogel and nanofiber complex is fabricated aimed for such use. Cell encapsulation potential was demonstrated by seeding fibroblasts on this micro architecture and protein release was compared by loading BSA confirming protein delivery. Resulting hydrogel-nanofiber micro structure showed controllable release and high cell viability. |
| 저자 |
조강희, 고원건, 한상원, 김민수, 국윤민, 차성호, 윤병주
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| 소속 |
연세대 |
| 키워드 |
Microparticle; Hydrogel; Nanofiber; Cell encapsulation; Protein delivery
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| E-Mail |
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