| 학회 |
한국고분자학회 |
| 학술대회 |
2021년 봄 (04/07 ~ 04/09, 대전컨벤션센터) |
| 권호 |
46권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Preparation of hydrogel adhesive with high mechanical/adhesion properties and application for a drug delivery system |
| 초록 |
Poly(acrylic acid) (PAA) hydrogel is widely used as biomedical materials due to their biocompatibility. However, hydrogel has disadvantages of low mechanical and adhesion properties. We fabricated a UV-curable hydrogel adhesive with high tack property, peel strength, and adhesive force by adding additives. Herein, the modified cellulose nanofiber (m-CNF) and silica nanoparticles (SNPs) were exploited as additives to increase the internal cohesion of hydrogel adhesive introducing physical bonding networks between the carboxymethyl group of m-CNF and the hydroxyl group of the SiO2 NPs in the hydrogel. Furthermore, cytotoxicity test and drug release test ascertained that hydrogel has an availability as a drug carrier. According to the results, it was expected that this hydrogel nanocomposites could be applied as transdermal drug delivery system. |
| 저자 |
하채명1, 이지영1, 이욱상1, 남기범2, 이동윤1
|
| 소속 |
1경북대, 2고분자공학과 |
| 키워드 |
hydrogel; adhesive
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| E-Mail |
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