화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2007년 봄 (04/19 ~ 04/20, 울산 롯데호텔)
권호 13권 1호, p.431
발표분야 생물화공
제목 Self regulated insulin delivery system using pH-responsive liposomes
초록 We performed chemical modification glucose oxidase and characterized it. Glucose oxidase was hydrophobically modified with palmitic acid of N-hydroxysuccinimide ester. And then, it characterized the enzymatic activity, surface tension, and the number of covalently modified lysine residue. pH-sensitive liposome was prepared by phospholipid and hydrophobically modified glucose oxidase containing calcein. Fluorescence quenching % was determined.
저자 조성민, 김진철
소속 강원대
키워드 liposomes; glucose oxidase; ph-responsive
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