| 학회 |
한국공업화학회 |
| 학술대회 |
2022년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
26권 1호 |
| 발표분야 |
포스터-생체재료 |
| 제목 |
Bioactive glass-modified halloysite nanotubesreinforced hybrid hydrogels for hard tissue regeneration |
| 초록 |
Bone defects caused by fractures or diseases areserious clinical challenges because of they fail to heal naturally and need abiomaterial-based scaffold to enable bone regeneration. The search fordeveloping an appropriate scaffold for bone regeneration is still unaccomplished.Hydrogel as three-dimensional (3D) polymeric-network may provide a suitable 3Dmicroenvironment for the regeneration of damaged bone tissues. However, the useof hydrogels in bone tissue regeneration is restricted due to their lowmechanical properties as well as imperfect angiogenic-osteogenic events, posingchallenges in designing efficient hydrogels with strong mechanical attributeand adequate bioactivity. In our study, we synthesized polyacrylamide-basedhydrogels by involving polysaccharides and bioactive glass-modified halloysitenanotubes. As-obtained hydrogels showed enhanced mechanical properties, in vitro bioactivity(i.e. apatite formation) and satisfactory in vitro cellularresponse. |
| 저자 |
ANUJ KUMAR, Ankur Sood, 한성수
|
| 소속 |
Yeungnam Univ. |
| 키워드 |
Hydrogels; polyacrylamide; polysaccharide; bioactive glass; halloysite nanotubes; bone tissue engineering
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| E-Mail |
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