| 학회 |
한국고분자학회 |
| 학술대회 |
2020년 가을 (10/05 ~ 10/08, 부산컨벤션센터(BEXCO)) |
| 권호 |
45권 1호 |
| 발표분야 |
Korea-Taiwan Joint Symposium: Advanced Polymer Science and Engineering (English) |
| 제목 |
Synthesis and Hydrogelation of Polypeptide-Based Polymers |
| 초록 |
Polypeptide-based copolymers recently have attracted increasing interest due to their biodegradability/biocompatibility, ordered chain conformation, stimuli-responsiveness, and possibly biological functions. We report the synthesis and hydrogelation of block copolypeptides in solution. The hydrogelation was determined by the packing of the polypeptide assemblies, dictated by the balance between the intermolecular hydrogen bonding interactions and charge repulsion exerted respectively by sheet-like and positively charged polypeptide segments. These noncovalent interactions can be manipulated by varying polypeptide chain composition and conformation as well as topology, which governed their critical gelation concentration, gel molecular assembly, and gel mechanical property. This study reveals that sheet-like segments can trigger the self-assembly and hydrogelation of polypeptides. |
| 저자 |
Jeng-Shiung Jan1, Xuan-You Shen2, Chen-Chi Tang1
|
| 소속 |
1Department of Chemical Engineering, 2National Cheng Kung Univ. |
| 키워드 |
- |
| E-Mail |
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