| 학회 |
한국재료학회 |
| 학술대회 |
2013년 봄 (05/23 ~ 05/24, 여수 엠블호텔(THE MVL)) |
| 권호 |
19권 1호 |
| 발표분야 |
D. 바이오재료(Biomaterials) |
| 제목 |
Bone formation and degradation of a highly porous Gelatin-Pectin-biphasic calcium phosphate composite in presence of BMP-2, VEGF |
| 초록 |
In this study, composite of Gelatin (Gel)-Pectin (Pec)-biphasic calcium phosphate (BCP), BMP2-Gel-Pec-BCP and VEGF-Gel-Pec-BCP scaffolds were fabricated successfully for bone regeneration. The incorporating of bone morphogentic protein (BMP-2 ) and vascular enthedlidal growth factor (VEGF) promoted osteoinduction in Gel-Pec-BCP was developed for bone induction. The physical properties were examined by scanning electron microscopy (SEM), porosity, Fourier transform infrared spectroscopy(FT-IR) and X-ray Diffraction (XRD). In vitro experiment was done by studying of cytotoxicity using MTT assay, and immuneflourescene for cell behaviour. Based on the results, it is concluded that our modified scaffolds hold a great candidate for bone tissue engineering application. |
| 저자 |
Jhaleh Amirian1, Nguyen Thuy Ba Linh2, Young Ki Min3, Hun-Mo Yang1, Byong-Taek Lee2
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| 소속 |
1Department of Biomedical Engineering and Materials, 2College of Medicine, 3Soonchunhyang Univ. |
| 키워드 |
Gelatin; Pectin; biphasic calcium phosphate; BMP-2; VEGF
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| E-Mail |
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