| 학회 |
한국재료학회 |
| 학술대회 |
2013년 봄 (05/23 ~ 05/24, 여수 엠블호텔(THE MVL)) |
| 권호 |
19권 1호 |
| 발표분야 |
D. 바이오재료(Biomaterials) |
| 제목 |
Natural Bio Polymer Coating on BCP Surface to Evaluate the Comparative Osteogenic Potential. |
| 초록 |
In this work, we fabricated BCP disks using an uniaxial press machine and sintered by microwave heating at 1350°C. Then the BCP disks were coated with either collagen, hyaluronic acid and bovine serum albumin (BSA). Coating morphology was evaluated by SEM. Coating stability and dissolution behavior were observed with exposure to culture media and water uptake measurement. Surface elemental composition of the coated disks was evaluated by X-ray photoelectron spectroscopy (XPS). Cytotoxycity, cell proliferation, ALP activity, differentiation behavior, western blot, RT-PCR were carried out to investigate the in vitro behavior of MC3T3-E1 cells. The coated BCP substrates showed superior bio-compatibility compared to the bare BCP surface. The study elucidates a comparative analysing of the natural biopolymers as a stimulating agent for bone graft scaffold. |
| 저자 |
Hyoung-Seok Kim1, Swapan Kumar Sarkar2, Celine Abueva3, Young-Ki Min4, Hun-Mo Yang5, Byong-Taek Lee1
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| 소속 |
1Department of Biomedical Engineering and Materials, 2College of Medicine, 3Soonchunhyang Univ., 4Chungnam 330-930, 5Korea |
| 키워드 |
BCP; Gelatin; Collagen; Hyaluronic acid; Chondroitin sulphate; BSA; In vitro
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| E-Mail |
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