| 학회 |
한국공업화학회 |
| 학술대회 |
2019년 가을 (10/30 ~ 11/01, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
23권 2호 |
| 발표분야 |
포스터_생체재료 |
| 제목 |
Improvement of Osteoconductivity of Biodegradable PLCL Bone Cement |
| 초록 |
Human bone-related disease, such as osteoporosis and arthritis, is continuously increasing problem in elderly population. This illness is caused due to the lack of calcium arising from demineralization of bone tissue and brings about serious deterioration of physical structure of bone. In this investigation, we synthesized PLCL(5:5) via copolymerization of lactide and caprolactone monomers. highly porous PLCL scaffolds combined with ceramic particles were fabricated to use as bone cement possessing improved physical and biological properties. Various properties including mechanical strength, chemical state, hydrophilicity, and water uptake were examined using SEM, EDX, and FT-IR. The biological property of the scaffold was evaluated with regard to proliferation of osteoblastic sarcoma cells. Results demonstrate that both mechanical and biological functionality were significantly improved, suggesting the developed scaffold can be potentially applied for the preparation of bone grafts. |
| 저자 |
박진우, 김정헌, 박이안, 임예람, 홍재윤, 이우걸
|
| 소속 |
단국대 |
| 키워드 |
PLCL; Horsebone; CaP; Cement; MG-63
|
| E-Mail |
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