| 학회 |
한국화학공학회 |
| 학술대회 |
2008년 봄 (04/23 ~ 04/25, 제주ICC) |
| 권호 |
14권 1호, p.104 |
| 발표분야 |
고분자 |
| 제목 |
Synthesis and Characterization of pH-Sensitive Hydrogel Microparticles in Supercritical Carbon Dioxide |
| 초록 |
Supercritical carbon dioxide is considered as a useful alternative of toxic or volatile organic solvents for polymer synthesis and processing. The use of supercritical CO2 (scCO2) as a solvent for polymerization is attractive since a polymerization medium are less-toxic, non-flammable, chemically inert and naturally abundant than many other organic solvents, the product may be easily collected from solution after processing, and the polymerization rate is promoted as the diffusion of monomer in the polymer particle is enhanced. In this study, we synthesized pH-sensitive P(MAA-co-EGMA) hydrogel particles with micro- and nano- scales using supercritical carbon dioxide. In order to evaluate the feasibility of the P(MAA-co-EGMA) hydrogel microparticles for intelligent drug delivery applications, the pH-sensitive swelling and release behavior in response to the external pH changes was investigated. |
| 저자 |
양주승1, 류원선1, 이상민2, 김규식2, 최문재2, 김범상1
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| 소속 |
1홍익대, 2네비온 주식회사 |
| 키워드 |
pH-Sensitive Hydrogel; Supercritical Carbon Dioxide
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| E-Mail |
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| 원문파일 |
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