화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2007년 봄 (04/19 ~ 04/20, 울산 롯데호텔)
권호 13권 1호, p.382
발표분야 생물화공
제목 Different Amniotic Epithelial Cells from Different Amnion Site
초록 Recently some researchers reported that some stem cells exist on and can be isolated from human amnion and amniotic fluid. It is known amniotic epithelial cells (AECs) have some characteristics of stem cells, which could differentiate into ectodermal epidermis, hair follicle and endodermal hepatocyte-like cells, insulin-producing cells. However, the exact origin of the AECs is not clarified in previous reports. So, in this study, we tried to isolate AECs from different amnion site and confirm whether these different AECs have same characteristics or not.
AECs isolated from different amnion site showed same proliferation capacity. However, the isolation success rate was very different from different amnion site; placental < transitional < cord amnion. AECs from different amnion site did not have same characteristics in the point of in situ proliferation and stratification view. However, the isolated AECs had same proliferation and differentiation (into hepatocyte) capacity. It is not clear why these differences come from, so it will be necessary to investigate their different characteristics and reasons.
저자 정보영1, 윤희훈1, 안재일1, 김영진2, 송계용3, 박정극1
소속 1동국대, 2라이프코드, 3중앙대
키워드 amnion; epithelial cell; culture; anatomical site
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