| 초록 |
Iron oxide nanoparticles with suitable biocompatible coatings have been widely used for magnetic resonance imaging. The goal of this study is to synthesize cancer targeted imaging agents detectable by MRI and fluorescence. In this study, polysaccharide-coated magnetite nanoparticle (SNP) was modified with oligo-peptide and FITC, the crystallinity, magnetic property, size and shape of the SNP were determined by X-ray diffrectometer (XRD), Vibrating Sample Magnetometer (VSM), Transmission Electron Microscopy (TEM) and Dynamic Light Scattering (DLS). Fluorescence and confocal microscopy were also used to visualize the uptake and the distribution of the modified nanoparticles into the cells. |
